First 48: an indica strain with 22% THC, known for relaxed, euphoric, sleepy.
0–100 profile derived from cannabinoids, effects, and terpenes.
First 48 blends The White × Orange Kush into an indica strain at 22% THC. Myrcene-rich profile: relaxed, euphoric, sleepy. Taste: citrus, earthy
For First 48, seek Myrcene-dominant cuts with a clean night finish. citrus notes signal quality. Shines for evening relaxation.
Pro tip: First 48 from Unknown often tests higher in relaxed than imports. Myrcene varies wildly between phenotypes — look for >0.5% Myrcene.
Northern Lights blends Afghani × Thai into an indica strain at 16% THC. Myrcene-rich profile: relaxed, sleepy, uplifted. Taste: sweet, earthy, pine. For insomnia, stress, pain. Score: 8/10.
A indica cross of Landrace, Hindu Kush tests ~18% THC with a Myrcene nose. relaxed, sleepy, euphoric, flavors of earthy, sweet, pine. Used for pain, insomnia, nausea. Score: 7.8/10.
A indica cross of Hindu Kush × Skunk, Master Kush tests ~20% THC with a Myrcene nose. relaxed, uplifted, sleepy, flavors of earthy, citrus, woody. Used for stress, pain, insomnia. Score: 8.3/10.
London Pound Cake is an indica strain from Sunset Sherbet × Nepali Kush. THC ~26%, dominant Myrcene, delivering relaxed, sleepy, uplifted. Flavor: grape, berry, lemon. Aroma: grape, citrus, earthy. Used for stress, pain, insomnia. Score: 9/10.
Ice Cream Cake delivers an indica experience from Wedding Cake × Gelato 33. At 23% THC, Limonene-led, bringing relaxed, sleepy, uplifted. Taste: vanilla, cream, sweet. Medical: insomnia, pain, stress. Score: 8.5/10.
Gelato Cake delivers an indica experience from Gelato 33 × Wedding Cake. At 24% THC, Limonene-led, bringing relaxed, sleepy, uplifted. Taste: vanilla, berry, sweet. Medical: insomnia, pain, stress. Score: 8.8/10.
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Relative prominence based on the strain profile.
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Parents: The White × Orange Kush
Best reserved for night or before-sleep use. The heavy physical sedation locks the body and helps transition into natural REM cycles.
Medical marijuana patients frequently turn to First 48 to help manage symptoms associated with stress, pain, anxiety. The strain's relaxed and euphoric properties are reported to help ease tension, reduce physical discomfort, and lift mood without causing excessive grogginess.
Evidence level: high — Backed by extensive clinical research surveys confirming cannabinoids alleviate persistent nerve discomfort.
Immediate head calm. A warm physical wave washing down the neck and shoulders, releasing joint tension.
Physical weight sets in. You will feel comfortable sinking into cushions, with stress melting away.
Deep sedation peak. Couch-lock occurs alongside strong appetite stimulation. Best time to put on a movie.
Mellow wind-down. Cerebral buzz settles into a peaceful, clear-headed calm. No hard crash.
Typical duration: 2.5 to 3.5 hours
Mental: Calm, slow, peaceful, free from stress thoughts.
Body: Heavy limbs, floating sensation, pain relief, hungry.
Enthusiasts looking for deep evening comfort, chronic pain relief, and help with sleeplessness.
Avoid this strain if you need to remain active, drive, or focus on detailed administrative tasks, as it induces muscle heaviness.
The secret to unlocking the full potential of First 48 lies in temperature control. To preserve its delicate Myrcene terpenes, vaporize at 334°F (168°C) rather than combusting. This triggers the entourage effect, blending its 22% THC with secondary cannabinoids. Highly sedating, this strain is best reserved for late nights or as a bedtime wind-down. Keep snacks nearby, as it is known to stimulate appetite. Beginners should start with a single inhalation due to its fast-acting onset, while seasoned users can appreciate its deep, multi-layered terpene depth.
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